The Dextop application framework allows you to create Rich Internet Applications based on .NET/Mono and Sencha Ext JS. It has proven to be useful for online business applications. It features a desktop-like Ext JS frontend, simplified client-server communication, a stateful programming model, real-time updates and notifications from the server, automatic column model generation, automatic store model generation, and automatic form generation.
Vici MVC is a MVC Web application framework for .NET 2.0 or higher. It runs on the low-level ASP.NET layer provided by the .NET framework, but does not use ASP.NET WebForms and Controls. The framework is controller-centric as opposed to the view-centric architecture of ASP.NET WebForms. This allows Web applications to be built according to the MVC pattern with minimal effort. Vici MVC emphasises complete separation of concerns, ease of use, minimal configuration requirements, integration with any data access technology, performance, and easy deployment ("XCOPY deployment").