Tcl provides a portable scripting environment for Unix, Windows, and Macintosh that supports string processing and pattern matching, native file system access, shell-like control over other programs, TCP/IP networking, timers, and event-driven I/O. Tcl has traditional programming constructs like variables, loops, procedures, namespaces, error handling, script packages, and dynamic loading of DLLs. Tk provides portable GUIs on UNIX, Windows, and Macintosh. A powerful widget set and the concise scripting interface to Tk make it a breeze to develop sophisticated user interfaces.
GTK, which stands for the Gimp ToolKit, is a library for creating graphical user interfaces. It is designed to be small and efficient, but still flexible enough to allow the programmer freedom in the interfaces created. GTK provides some unique features over standard widget libraries.
Zune is a free clone of the famous MUI (Magic User Interface) toolkit from the Amiga. It is primarily designed for C, and uses BOOPSI as an object-oriented layer. The MUI-apps developer should not care about "precise" graphic design (to let the user fully customize its application), and not care about resize (smart automatic layout algorithm). The MUI-apps user has maximum control over applications look and feel, and he can customize apps either globally or individually through a graphical prefs program.
Qt is a comprehensive, object-oriented development framework that enables development of high-performance, cross-platform rich-client and server-side applications. When you implement a program with Qt, you can run it on the X Window System (Unix/X11), Apple Mac OS X, and Microsoft Windows NT/9x/2000/XP by simply compiling the source code for the platform you want. Qt is the basis for the KDE desktop environment, and is also used in numerous commercial applications such as Google Earth, Skype for Linux, and Adobe Photoshop Elements.
FOX is a C++-based toolkit for GUI development. It includes a rich set of widgets and has powerful yet simple layout managers, MDI widgets, and mega-widgets. FOX incorporates support for XDND for drag and drop, X clipboard and X Selection, watching other I/O channels and sockets, timers and idle processing, object serialization and deserialization, a registry to save persistent settings, and 3D widgets using Mesa or OpenGL. FOX works on Linux, IRIX, Solaris, HP/UX, AIX, Tru64 Unix, Windows 9x,NT,2K (VC++, GNUWIN32, Borland, VisualAge C++), FreeBSD, and Sequent.
FLTK (pronounced "fulltick") is a cross-platform C++ GUI toolkit for UNIX/Linux (X11), Microsoft Windows, and Mac OS X. It provides modern GUI functionality without the bloat, and supports 3D graphics via OpenGL and its built-in GLUT emulation. FLTK is designed to be small and modular enough to be statically linked, and also works fine as a shared library. It also includes an excellent UI builder called FLUID that can be used to create applications in minutes.