NOCC is a simple and fast Web-based e-mail reader which can handle POP3, SMTP, and IMAP servers. It is written with PHP5, and uses sessions, has low requirements (no database, frames), and is easy to install. It also features multi-language support, MIME attachment decoding/encoding, and the ability to display HTML messages.
phlyMail is a groupware, webmailer, and PIM. It offers unlimited nested groups, unlimited POP3/IMAP profiles, quotas, an integrated address book, a calendar with multiple reminders and event repetitions, a file manager with an integrated WebDAV server, the ability to send faxes, SMS support (which lets you send SMS, get reminded of events via SMS, and get email notification via SMS), a bookmark manager, themes, and multilingual support. It uses either sendmail or SMTP to send email, and can handle MIME and SSL connections. Support for IDN (Internationalized Domain Names) is included. Through its modular design, it's easy to add completely new features as modules, which can be plugged into the system.