TweetBox.fx is a Twitter desktop client. It lets users send updates, replies, and direct messages. Users can retrieve their friend's timeline, their own timeline, direct messages, replies, and their favorites. TweetBox also allows the user to view multiple timelines at the same time. TweetBox has a very user friendly entry box for typing updates. It shows you how many characters are left and provides a very easy-to-use URL-shrinking function. TweetBox can also detect links to pictures on Mobypicture and TwitPic and respond by showing, instead of the original URL, a link labeled "picture" that pops up a thumbnail when the mouse hovers over it.
Histwi is a Linux desktop program for Twitter account management. It allows you to download and save all your Tweets to a database, view and export all saved Tweets to HTML or text files, compare your Following to Followers, follow/unfollow any your friends, track new followers and unfollowers, and manage multiple Twitter accounts.