Roundcube Webmail is a browser-based, multilingual IMAP client with an application-like user interface. It provides the full functionality you expect from an email client, including MIME support, address book, and folder manipulation. High extensibility is granted by the plugin API and the user interface is fully skinnable using XHTML and CSS 2.
Drivel is a GNOME client for working with online journals, also known as weblogs or simply blogs. It retains a simple and elegant design while providing many powerful features, including support for LiveJournal, Blogger, MovableType, Advogato, and Atom journals. (Systems based off these are also supported, including WordPress and Drupal.)
elRTE is a WYSIWYG HTML editor for the Web written using jQuery. It features rich text editing, options for changing its appearance and style, insertion and management of various HTML elements with formatting (images, tables, lists, etc.), support for viewing and editing HTML code, and normal and full-screen modes.
AfterLogic WebMail Lite PHP is a Webmail script with a modern AJAX interface. It supports IMAP accounts, SMTP, and SSL (including Gmail). Users can check and send mail and use an address book. It provides a slick skin, a three-pane view, non-English language support, UTF-8 support, IMAP folders, and viewing and composing HTML mail. A MySQL backend is supported, with Web-based administration and installation and cPanel/Plesk/DirectAdmin integration.