Beast is a powerful music composition and modular synthesis application. It offers multiple input methods like multitrack, piano roll, and pattern editing and supports skins. On the technical side, it has a wide range of abilities like sequencing, unlimited undo/redo history, real-time synthesis with multiprocessor support, full duplex 32-bit audio rendering, precise timing down to sample granularity, on demand loading of partial wave files, on the fly decoding of various sample formats, aliasing free oscillators, and full Scheme scripting support.
jMax is a visual programming environment for building interactive real-time musical and multimedia applications by allowing the user to interactively design dataflow circuits. The basic data types that can go through are integers, symbols, lists, etc. It is an event-driven system and has been used for MIDI processing. A second part of the system (DSP) allows a continuous signal to flow through a circuit, which is most useful for PCM sound (ie. microphone, sound files, etc.). The system is extensible by using shared libraries, you may add data processor types, data types, GUI elements, device types, and more. Data processors may also be designed as circuits and reused.
Scheme Note is a Scheme-like music file format and MIDI conversion tool. It takes a text file, which is a representation of a song, loosely tied to a MIDI-like event structure, and outputs a corresponding MIDI file. It is hand-editable for simple songs, and should be very easy to parse for a GUI.