Isabelle is a popular generic theorem prover developed at Cambridge University and TU Munich. Existing logics like Isabelle/HOL provide a theorem proving environment ready to use for sizable applications. Isabelle may also serve as framework for rapid prototyping of deductive systems. It comes with a large library including Isabelle/HOL (classical higher-order logic), Isabelle/HOLCF (Scott's Logic for Computable Functions with HOL), Isabelle/FOL (classical and intuitionistic first-order logic), and Isabelle/ZF (Zermelo-Fraenkel set theory on top of FOL).
MLton is a whole-program optimizing Standard ML compiler. It generates standalone executables with excellent runtime performance, supports the full SML 97 language, and has a complete basis library. It also has a fast C FFI, source-level time and allocation profiling, and many useful libraries.
sml/nj (Standard ML of New Jersey) consists of a compiler, compilation manager, and libraries for Standard ML. Included are CML (Concurrent ML) and eXene (a toolkit for X based on CML). The compiler produces efficient code for most popular architectures (Intel x86, Sparc, Alpha, Mips, HP-PA, PowerPC) and runs under Unix, Linux, or Windows (95,98,NT).