CMUCL is a free, high performance implementation of the Common Lisp programming language which runs on most major Unix platforms. It mainly conforms to the ANSI Common Lisp standard. CMUCL provides a sophisticated native code compiler; a powerful foreign function interface; an implementation of CLOS; the Common Lisp Object System; which includes multimethods and a metaobject protocol; a source-level debugger and code profiler; and an Emacs-like editor implemented in Common Lisp. CMUCL is maintained by a team of volunteers collaborating over the Internet, and is mostly in the public domain.
ILISP is a package that is designed to integrate various Lisp implementations (mostly Common Lisp systems and various Scheme dialects, including Guile) within Emacs (or XEmacs). ILISP runs an inferior Lisp process (in Emacs parlance) and provides a specialized set of commands, key bindings, and menus to ease the interaction with it. ILISP commands access the underlying Lisp process and provide ways to make the editing, compilation, and execution of Lisp programs much easier.