MuseScore lets you notate and compose music easily with your keyboard, your mouse, or a MIDI keyboard. You can print beautifully engraved sheet music or export it as PDF or PNG. You can play your score, transpose it, and save it as audio or MIDI file. MuseScore also supports MusicXML to let you share your composition with other scorewriters. MuseScore is often advertised as a cost effective alternative for Sibelius and Finale.
mtPaint is a simple GTK+1/2 painting program designed for creating icons and pixel-based artwork. It can edit indexed palette or 24 bit RGB images and offers basic painting and palette manipulation tools. Its main file format is PNG, although it can also handle JPEG, GIF, TIFF, BMP, TGA, XPM, and XBM files.
Tux Paint is a simple and entertaining drawing program geared towards young children. It has a simple interface, sound effects, and a cartoon character (Tux, the Linux penguin). Along with drawing brush strokes, lines and shapes, you can also enter text and place "rubber stamp" (or "sticker") images on the picture. Tux Paint is extensible, and could be useful in an educational environment (such as a grammar, elementary, or grade school). It's portable across numerous platforms, and runs well even on slower systems like the Pentium 133MHz.
QCad is a powerful but easy to use 2D CAD program for Linux, Windows, and Mac OS X. It uses DXF as its standard file format. While other CAD packages are often rather complicated to use, QCad tries to stay comfortable, and even an absolute beginner can create professional drawings with a minimum of effort.