AfterLogic WebMail Lite PHP is a Webmail script with a modern AJAX interface. It supports IMAP accounts, SMTP, and SSL (including Gmail). Users can check and send mail and use an address book. It provides a slick skin, a three-pane view, non-English language support, UTF-8 support, IMAP folders, and viewing and composing HTML mail. A MySQL backend is supported, with Web-based administration and installation and cPanel/Plesk/DirectAdmin integration.
SOGo is a very fast and scalable modern collaboration suite (or groupware). It offers calendaring, address book management, and a full-featured Webmail client along with resource sharing and permission handling. It also makes use of documented standards (IMAP, CalDAV, CardDAV, etc.) and thereby provides native connectivity (without plugins) to many clients such as Microsoft Outlook, Apple iCal, the iPhone, Mozilla Lightning, and a plethora of mobile devices via SyncML. It can reuse any existing email and database infrastructure, avoiding long hours of site restructuring.
Horde Groupware Webmail Edition is an enterprise ready browser-based communication suite. Users can read, send, and organize email messages and manage and share calendars, contacts, tasks, and notes with the standards compliant components from the Horde Project. It bundles the separately available applications IMP, Ingo, Kronolith, Turba, Nag, and Mnemo. It can be extended with any of the released Horde applications or the Horde modules that are still in development, like a file manager, a bookmark manager, a forum, or a wiki.
Roundcube Webmail is a browser-based, multilingual IMAP client with an application-like user interface. It provides the full functionality you expect from an email client, including MIME support, address book, and folder manipulation. High extensibility is granted by the plugin API and the user interface is fully skinnable using XHTML and CSS 2.
MIMP is a version of the popular webmail client IMP intended for mobile phones and PDAs. Basic webmail functionality is implemented, including mailbox viewing and paging, viewing messages, deleting, replying, forwarding, and composing new messages. It utilizes the Horde Application Framework.
Thunderbird is a total redesign of the Mozilla mail component to produce a cross-platform, stand-alone mail application using the XUL user interface language. It has many new features, among them the ability to customize your toolbars the way you want them. a new look and feel with a large number of downloadable themes which alter the appearance of the client, and the ability to add UI extensions.
GroupOffice is a groupware suite that takes your office online, implementing online collaboration and CRM. It allows you to share projects, calendars, files and email online with co-workers and clients. It is easy to use and fully customizable. It also features synchronization with PDAs and Outlook.
phlyMail is a groupware, webmailer, and PIM. It offers unlimited nested groups, unlimited POP3/IMAP profiles, quotas, an integrated address book, a calendar with multiple reminders and event repetitions, a file manager with an integrated WebDAV server, the ability to send faxes, SMS support (which lets you send SMS, get reminded of events via SMS, and get email notification via SMS), a bookmark manager, themes, and multilingual support. It uses either sendmail or SMTP to send email, and can handle MIME and SSL connections. Support for IDN (Internationalized Domain Names) is included. Through its modular design, it's easy to add completely new features as modules, which can be plugged into the system.