GIMP is the GNU Image Manipulation Program. It is a freely distributed piece of software suitable for such tasks as photo retouching, image composition and image authoring. It can be used as a simple paint program, an expert quality photo retouching program, an online batch processing system, a mass production image renderer, a image format converter, etc.
SIP provides image processing, pattern recognition, and computer vision routines for SciLab, a Matlab-like matrix-oriented programming environment. SIP is able to read/write images in almost 90 major formats, including JPEG, PNG, BMP, GIF, FITS, and TIFF. It includes routines for filtering, segmentation, edge detection, morphology, curvature, fractal dimension, distance transforms, multiscale skeletons, and more.
XPaint is an easy-to-use image editor which supports many standard and less standard paint procedures that demanding non-professional users would expect. It includes several advanced features like image processing algorithms, programmable C scripts, simultaneous editing of multiple images, and supports a wide variety of image formats.
F-Spot is a personal photo management application for the GNOME desktop. It simplifies digital photography by providing intuitive tools to help you share, touch-up, find, and organize your images. These tools include editing, color adjustments, tags, Photo CD creation, and exporting for upload.
Gimp User Filter is a work-alike to Adobe's Filter Factory. It is a generic image processing plug-in that can be used to create new filters for The GIMP without having to go through the process of learning about The GIMP's SDK. Many freely available filters that have been created for Filter Factory can also be used with this plug-in.
Allegro Sprite Editor (ASE) is a program specially designed with facilities to create animated sprites that can be used in some video game. It lets you create static images, characters with movement, textures, patterns, backgrounds, logos, color palettes, etc. It focuses on pixel editing to do pixel art. It isn't a photo retouching tool or a vector graphics editor. Mainly, it is a tool to create tiny animations pixel-by-pixel.