PySite is not a CMS in the traditional sense. Rather, you manage the contents of a Web site via a file manager interface, which gives you access to all settings (pages, styles, plugins, etc.). Compose your pages with Jinja templates, and edit your code comfortably with syntax highlighting in the ACE editor. You may write your stylesheets in Sass and let the integrated compiler write CSS files. PySite also contains a facility to manage virtual mailboxes, in case you maintain your own SMTP and IMAP server, e.g. with Postfix and Dovecot.
Q-Tubes is a Web-based QEMU/KVM machine manager in Python built around the Pyramid Web framework. Its goal is to allow management of QEMU/KVM networks across single host instances, and ultimately across server farms. It supports minimal VM instances with disk support and basic network configuration (no user-space network yet), and basic VDE switch configurations. It provides a WSGI interface for deployment behind WSGI-aware servers, or provides its own basic server (python-waitress) for simple instances. The application is under steady development and has a moderate number of (Python) dependencies. Installation in a virtualenv is strongly recommended. It requires QEMU/KVM, VDE, and Python 2.7 or later.