mod_sphinx is an Apache module which intercepts output bound for the client, whether it be from files served by the same Web server, files sent via reverse proxying, or files delivered by transparent forward proxying (outbound proxying, as in your browser's proxy setting). It opens the text and replaces a word with another word or phrase. When in regular proxy mode, it cannot modify SSL content since Apache cannot decrypt that (it would be a protocol violation).
Quassel IRC is a modern, cross-platform, distributed IRC client, meaning that one or more clients can attach to and detach from a central core, much like the popular combination of screen and a text-based IRC client, but graphical. In addition to this unique feature, it aims to be a comfortable chatting program.