ResearchMaster is a tool that you can trust to help with organization, multitasking, and research, both personal and professional. It provides a place to capture your fleeting thoughts and ideas, and it allows you to hit the ground running on projects. It was developed with professional scientific research in mind, but it's great for grocery lists and address books as well.
Project'Or RIA is project management software that tries to to gather in a single tool all functionality needed to organize your projects. It focuses on IT projects, but is also compatible with all kinds of other projects. The objective is to keep it simple and easy to use on a day to day basis.