CoaSim is a tool for simulating the coalescent process with recombination and gene conversion under the assumption of exponential population growth. It efficiently constructs the ancestral recombination graph for a given number of individuals and uses this to simulate samples of SNP and micro satellite haplotypes/genotypes. The generated sample can afterwards be separated in cases and controls, depending on the states of selected individual markers. The tool can accordingly also be used to construct cases and control data sets for association studies.
ProActive is a Java library for parallel, distributed, and concurrent computing as well as mobility and security in a uniform framework. It provides a comprehensive API and a graphical interface and is based on an Active Object pattern, a uniform way to encapsulate a remotely accessible object, a thread as an asynchronous activity, an actor with its own script, a server of incoming requests, a mobile and secure agent, and a component with server and client interfaces. It simplifies the programming of applications distributed over a LAN, clusters, an intranet, or Internet GRIDs.
The National Library of Medicine Insight Segmentation and Registration Toolkit (ITK) is a software system to support the Visible Human Project. Segmentation is the process of identifying and classifying data found in a digitally sampled representation. Registration is the task of aligning or developing correspondences between data. For example, in the medical environment, a CT scan may be aligned with an MRI scan in order to combine the information contained in both.
Cell Electrophysiology Simulation Environment is a framework to perform electrophysiological simulations. It can, for example, simulate cardiac myocyte electrical activity. It is useful for simulations of action potentials, individual ionic currents, and changes in ionic concentrations.
FastVox is an API for volume visualization that can be embedded into OpenGL displays. It features a multi-threaded realtime volume rendering engine which is based on a set of plugins that range from high-speed software-based renderers to hardware-accelerated renderers designed for current generation graphics hardware.
The OpenVL library is a framework for working with 3D volumetric datasets. It provides a standard and uniform API to volumetric data access, storage, and processing. It is designed and built to be fast, extensible, flexible, and easy to use. The library is completely open-sourced and encourages contribution. This library is an ideal choice if you want to write applications that deal with 3D volumes.