Cactus is a general, modular, parallel environment for solving systems of partial differential equations. The code has been developed over many years by a large international collaboration of numerical relativity and computational science research groups and can be used to provide a portable platform for solving any system of partial differential equations.
Calc is arbitrary precision arithmetic system that uses a C-like language. It's useful as a calculator, an algorithm prototype, and as a mathematical research tool. More importantly, calc provides a machine-independent means of computation. Calc comes with a rich set of builtin mathematical and programmatic functions.
CCMATH is a mathematics library, coded in C, that contains functions for linear algebra, numerical integration, geometry and trigonometry, curve fitting, roots and optimization, Fourier analysis, simulation generation, statistics, special functions, sorts and searches, time series models, complex arithmetic, and high precision computations.
distributed.net is a loosely knit group of computer users from all of the world that is taking up challenges requiring lots of computing power (most notably the RC5, DES, and OGR cracking contests). It is simple to participate in the challenges by downloading and running their client software (which uses idle CPU time to complete its tasks).
Genius is an arbitrary precision integer and multiple precision floating point calculator. It includes its own programming language similar in some aspects to C, bc, or Pascal. It can deal with rational numbers and complex numbers. It has matrix support as well. It uses the gmp library so it is very fast for calculations of large numbers. It has a command line and a GNOME interface. The GNOME interface supports plotting functions and 3D surfaces.