Dada Mail can help you manage a mailing list, offers complete support for safe, closed-loop opt-in subscriptions, sends out mass mailings, keeps an archive of your messages, and allows you to share your messages in many ways. It runs on your Web hosting account and you interact with it through your Web browser, making it available anywhere you have a connection to the Internet. You do not have to rely on a third-party list management system with costly monthly fees. It is rich with features, but tries to keep it simple. It is designed to favor flexibility, extensibility, and ease-of-use over core speed or extremely flashy but hard-to-use features. It is designed to be installed, set up, and understood by regular people who have Web sites, but has enough advanced features to entice more proficient users. If you've ever installed a bulletin board or blog software, you should be able to install Dada Mail without too many problems. Dada Mail can scale. You can install Dada Mail on most any basic hosting account and start sending out messages. If your mailing list grows large, you can switch to sending with a more powerful third-party system, like Amazon SES, where there's potentially no limit on the number of emails you may send, all without having to change mailing list management systems or your hosting.
Bulk Mailer helps speed the delivery of an email message to many recipients using Sendmail. It's best used in parallel with a mailing list manager such as Majordomo. For input, it takes a file of recipient addresses (one address per line) and a message (with headers already attached) to be sent to the recipients. It sorts the recipient list by reversed domain (so similar ones sort together), splits up the recipients into several groups containing no more than N domains each, creates an SMTP envelope for each group of recipients, and feeds each envelope to sendmail.
phplist is a mailing list and newsletter manager that allows posting via a Web page. It works well when used for announcements, and can handle very large email address lists. Users can sign up to multiple lists, but will only receive a single copy of cross-posted messages. When signing up, users can identify their geographical location, and messages can be targetted to these. You can add place holders in your email that will be replaced with personal details (such as the person's name). Users can update their own information, and unlike many other mailing list systems, they can change their email address. HTML emails are supported.
The Simple Mail Distributor is an Email::Filter-based Perl script which can be used to implement an administratively-managed mailing list. The service can be restricted to a list of allowed senders. Each message is sent individually with the To header adjusted to match the recipient.
pop3ml is a program to manage mailing lists and newsletters without a local SMTP server. It requires only a simple POP3 email account. It's highly configurable by users. You can subscribe or unsubscribe simply with email messages. There is optional subscription and unsubscription confirmation, subscription moderation, message moderation, digest message mode, parent/children list management, mail scheduling to postpone or repeat a message, a mail filter (with a procmail-like syntax), a message queue for unsent messages, message size check, a command to retrieve messages, bounce detection, message header management, black/white/allow/deny lists, and other functions. There is also a program to test list settings without sending any messages and another program to view and search through stored messages. You can configure it with programs like phpMyAdmin.