Gaze is a lightweight Gmail checker that sits in the system tray and notifies you of new messages in your inbox. You can configure how often the program will use the ROME API to check the Atom RSS feed for your inbox, as well as optional combined notifications, custom browser actions, theming, and more.
Trojita is a Qt IMAP email client. It is a pure Qt4 application with no additional dependencies. It has a robust IMAP core implemented using Qt's Model-View framework. Standards compliance is a design goal. It has support for bandwidth-saving mode aimed at mobile users with expensive connections. In addition to the usual SSL/TLS connections, the server can be accessed via SSH. It has on-demand body part loading, offline IMAP support, and safe dealing with HTML mail (actually more robust than Thunderbird's).
Bulk Mac Mail is an an application for sending personalized mass email messages. It allows you to use message templates with multiple custom fields from the recipient database inside your messages. Customer lists can be imported from files of any type. Since all messages go through the standard Apple Mail's message delivery framework, they are absolutely indistinguishable from the messages that were actually sent by Apple Mail.
Lamson is an SMTP server adopts a modern Web application framework design. Rather than bizarre flat file "databases" and hashtable stores, Lamson uses anything that Python does to store data, including Django's ORM, web.py's simple database library, Tokyo Tyrant, Lightcloud, Python's Shelve (not recommended), Raw SQLite3, SQLObject, CouchDB, Mongo DB, and SQLAlchemy.
mailxel is a personal mail store and mail client with a focus on the management and organization of high volume mail boxes. The main features are fast search, tagging, GTD inbox management workflow, efficient data storage, address management, automated server-side mail folder organization, and normal mail functionality (send, receive, forward, etc.).
OpenSMTPD is an RFC compliant, secure, and simple SMTP server ported from OpenBSD to Linux. It supports the SMTP protocol, including SSL versions for added security, virtual domains, forward files, and external delivery agents like procmail, and can do most of the basic things that other MTA implementations do.
S22.Imap is an easy-to-use and well-documented .NET library component for communicating with and receiving electronic mail from an Internet Message Access Protocol (IMAP) servers. It supports IMAP IDLE notifications and IMAP over SSL, allows selective fetching of parts of mail messages, is inherently thread-safe, and is well documented with lots of example code.
Masqmail is an MTA (mail transport agent) for notebooks, workstations, home servers, and generally any host with no permanent network connection. It has special support for multiple transfer routes (e.g. to different mail providers). Address rewriting can be done in several ways. It is a slim replacement for full-blown MTAs such as sendmail, exim, qmail, or postfix and for the intended uses, configuration is much simpler.