LigandScout allows for sophisticated 3D pharmacophore generation from macromolecule-ligand complexes, pharmacophore overlay and interpolation, and a lightning fast and robust pharmacophore-based alignment algorithm that allows creating consensus pharmacophores and merged feature pharmacophores.
AKVIS SmartMask plug-in is an efficient selection tool. There are two pencils: blue and red. You draw a line with the blue pencil inside the object you want to select, and with the red pencil some lines outside the object to define the areas that should be cut out. The plugin offers three modes: Sharp, Soft, and Complex.
HTCFlasher (formerly known as HERMflasher) is a tool which allows you to flash ROMs on most current HTC devices. It has some extra features that the original HTC RUU doesn't have. For example, it can present a serial prompt to the bootloader (replacing mtty), or it can dump NBH file contents (.nb ROM parts).
PylotLight is a cross-platform, themeable, plugin-supporting system for general computing tasks. It is comparable to QuickSilver, which you may recognize if you use a Mac. Current plugins exist for Web searches, Firefox bookmark launching, filesystem browsing and managing, subversion control, terminal control, and more.