pybonjour provides a pure Python interface (via ctypes) to Apple Bonjour and compatible DNS-SD libraries (such as Avahi). It allows Python scripts to take advantage of Zero Configuration Networking (Zeroconf) to register, discover, and resolve services on both local and wide-area networks. Since pybonjour is implemented in pure Python, scripts that use it can easily be ported to Mac OS X, Windows, Linux, and other systems that run Bonjour.
pydance is a dancing game written in Python, formerly named pyDDR. The idea is simple. There's a floor mat with arrows, and the game scrolls arrows up the screen to the beat while playing a song. When the arrows reach the top of the screen (not sooner and not later), the player hits the corresponding arrow on the pad, and given that it's hit on time with the beat, points are scored. Based on how well the dance is put together, s/he is graded at the end of the song. Both keyboard and mat play are supported.
The pylib library features the popular py.test command line tool for rapidly writing and running tests in Python and py.execnet, a new way to do ad-hoc distribution of Python code to remote processes. py.test runs well on Linux, Windows, and OSX using Python 2.4 through to 2.6. It can distribute a single test run to multiple machines. It is used in many projects, ranging from running tens of thousands of tests integrated with buildbot to a few inlined tests on a command line script.