libTISCH is a framework for easy development of multi-touch applications. It contains tools for video processing, calibration, gesture recognition and, most importantly, a GUI toolkit with widgets that utilize the multi-touch gestures detected by the lower layers. It runs on Linux, Mac OS X, and Windows.
reacTIVision is a computer vision framework for the fast and robust tracking of fiducial markers attached to physical objects, as well as for multi-touch finger tracking. It was mainly designed as a toolkit for the rapid development of table-based tangible user interfaces and interactive multi-touch surfaces such as the reacTable. Client application examples are available for various programming environments such as C++, Java, C#, Processing, PureData, Max/MSP, and Quartz Composer.
REALbasic is a cross-platform software development environment for developers who want to create and deliver native applications for Mac OS, Windows, and Linux. For example, you can create an application for Mac OS and Linux from a Windows machine. It is intended for people with all levels of programming experience. It is object-oriented, powerful, and supports advanced programming concepts like inheritance, polymorphism, interfaces, delegates, introspection, etc.
Gorm (Graphic Object Relationship Modeller) is a GNUstep application for building user interfaces and application objects relationships. Its major features include drag-and-drop creation of GUI elements from palettes, run-time loading of additional palettes, direct on-screen manipulation of GUI elements, manipulation and examination of objects via inspectors, and creation of connections between objects using mouse. It is a clone of the former NeXTstep (currently OS X) "Interface Builder" application.