BRL-CAD is a powerful constructive solid geometry solid modeling system that includes an interactive geometry editor, ray-tracing support for rendering and geometric analysis, path-tracing for realistic image synthesis, network distributed framebuffer support, and image and signal-processing tools.
Coin is an implementation of Open Inventor. Open Inventor is the de facto standard API for retained-mode 3D graphics programming. Open Inventor has a highly extensible design, and has been designed to allow for rapid development of highly interactive 3D graphics applications in the fields of CAD, engineering, scientific computing, simulation, VRML, and visualization.
OpenVRML is a VRML and X3D browser plug-in and C++ toolkit for incorporating VRML/X3D support into applications. It provides VRML97 and Classic VRML X3D parsers, a runtime, and an OpenGL renderer as C++ libraries. The renderer is fully separate from the runtime library so that users can also provide their own renderer. The OpenVRML browser is provided as a D-Bus service, and is embeddable in host applications using XEmbed. The distribution provides both a stand-alone host and a host that runs as a Mozilla plug-in.
VMD (Visual Molecular Dynamics) is designed for the visualization and analysis of biological systems such as proteins, nucleic acids, lipid bilayer assemblies, etc. It may be used to view more general molecules, as VMD can read standard Protein Data Bank (PDB) files and display the contained structure. VMD provides a wide variety of methods for rendering and coloring a molecule: simple points and lines, CPK spheres and cylinders, licorice bonds, backbone tubes and ribbons, cartoon drawings, and others. VMD can be used to animate and analyze the trajectory of a molecular dynamics (MD) simulation. In particular, VMD can act as a graphical front end for an external MD program by displaying and animating a molecule undergoing simulation on a remote computer. VMD uses OpenGL and OpenGL Programmable Shading Language for high performance rendering of large structures.
Ayam is a free 3D modelling environment for the RenderMan interface. It features good RIB export, CSG (all RenderMan primitives supported), and NURBS modelling. Features instancing, arbitrary number of modeling views, object clipboard, independent property clipboard, n-level undo, console, and Tree-View with Drag-and-Drop support.
The Interverse is the evolution and combination of the Web, chat, instant messaging (IM), and voice communication. It is not just a graphical user interface (GUI), but an immersive user interface (IUI). The Interverse is a virtual universe running on top of the Internet. It uses the Crystal Space 3D engine to render the user's view of the world.