The Chemistry Development Kit (CDK) is a library of Java classes for chemo-, bioinformatics, computational chemistry, and chemometrics. It provides important algorithms like substructure search, SMILES, Gasteiger charges, QSAR descriptor calculation, 3D structure generation, 2D layout and rendering, many IO formats, atom typing, and more.
imgSeek is a photo collection manager capable of searching through an image database, in which the query is expressed either as a rough sketch painted by the user or as another image you supply. You simply draw a rough sketch of what you want to find and imgSeek displays for you a thumbnail view of the best matches. You may also find duplicate images automatically, generate Web photo albums, edit image metadata including EXIF JPEG data, organize images into a keyword hierarchy, and more.