Open Tool Kit (Otk) is a portable widget library for making graphical user interfaces for C programs. It emphasizes simplicity for the application programmer without eliminating capability. Based on OpenGL, Otk supports Linux, Unix, and other OSs neutrally and efficiently. It is simple and compact, and it strives for easy compilation and linking to other applications. In seeking to address several issues associated with earlier graphics APIs, Otk explores some interesting methods, such as window-relative layout instead of pixel-based layout.
Mapnik is a toolkit for developing GIS applications. At the core is a C++ shared library providing algorithms/patterns for spatial data access and visualization. Essentially a collection of geographic objects (map, layer, datasource, feature, and geometry), the library doesn't rely on "windowing systems" and can be deployed in any server environment. It is intended to play fair in a multi-threaded environment and is aimed primarily, but not exclusively, at Web-based development. High-level Python bindings (boost.python) facilitate rapid application development, targeting zope3, django, etc.