Thunderbird is a total redesign of the Mozilla mail component to produce a cross-platform, stand-alone mail application using the XUL user interface language. It has many new features, among them the ability to customize your toolbars the way you want them. a new look and feel with a large number of downloadable themes which alter the appearance of the client, and the ability to add UI extensions.
The SeaMonkey project is a community effort to develop an all-in-one Internet application suite. It contains an Internet browser, email and newsgroup client with an included Web feed reader, HTML editor, IRC chat, and Web development tools, and is sure to appeal to advanced users, Web developers, and corporate users. It uses much of the Mozilla source code powering such successful siblings as Firefox, Thunderbird, Camino, Sunbird, and Miro.
Zimbra is a next-generation enterprise messaging and collaboration system. It features an Ajax Web client with conversation views, fast email search, Web service mash-ups, shared calendars, document authoring, and IM. The server also syncs to MS Outlook (via MAPI), the Apple desktop (via iSync, iCal, and CalDAV), POP/IMAP clients, and mobile devices (BlackBerry, smart phones, HTML Web browsers). A version of the Web client, Zimbra Desktop, also works offline with any POP/IMAP server. Administrators can control live backup/restores of individual or groups of mailboxes, hierarchical storage (HSM) and clustering, LDAP directory configuration, Web services integration with existing enterprise applications, and integrated anti-spam and anti-virus.
ADJE WebMail is a set of Perl CGI scripts which provide a Web interface to existing email accounts on any POP3-compliant email server. The software provides a complete interface, including encoding/decoding attachments, email and URL markup in received emails, and an address book for each user.
Xuheki is a fully featured email (IMAP) client for the Web. It looks and feels like an application rather than a Web site. It is fast, clean, and features no page reloads. It supports multiple users per installment, multiple IMAP servers per user, and multiple folders per IMAP server. It also supports text or HTML email, attachments, inline images, printing, and more. It has an "AJAX" interface that could compete with desktop-based mail user agents.