Quassel IRC is a modern, cross-platform, distributed IRC client, meaning that one or more clients can attach to and detach from a central core, much like the popular combination of screen and a text-based IRC client, but graphical. In addition to this unique feature, it aims to be a comfortable chatting program.
dxirc is a easy-to-use yet capable cross-platform IRC client. Among its notable features are flexible configuration, a fully customizable look independent of system-wide settings, multiple server support with optional automated joining of selected channels, and the ability to connect via SSL.
Gixaw Chat is a feature-rich system that adds live chat to your Web site. It features unlimited rooms, private and group chat, seamless Integration with any third-party application, easy file sharing, live image previews, powerful moderation (kick, ban user, and ban IP address), past chat transcripts, user profiles and display pictures, sound notifications, flood control, unlimited smileys, and a lot more.