The Chemistry Development Kit (CDK) is a library of Java classes for chemo-, bioinformatics, computational chemistry, and chemometrics. It provides important algorithms like substructure search, SMILES, Gasteiger charges, QSAR descriptor calculation, 3D structure generation, 2D layout and rendering, many IO formats, atom typing, and more.
The Interreality project is a collection of Open Source, Free Software projects based on the Virtual Object System (VOS) platform. The goal is to develop a free and open platform for multi-user 3D virtual reality games, applications, and interactive, collaborative 3D virtual spaces. VOS is a powerful and generic network object framework designed to support a variety of high-performance applications. It is the basis for Ter'Angreal, a general-purpose browser application for entering and participating in 3D worlds.
OGRE (Object-Oriented Graphics Rendering Engine) is a class library written in C++ designed to make it easier and more intuitive for developers to produce games and demos utilising 3D hardware. It exposes a number of useful objects allowing you to create and manipulate a 3D environment and render it to your specifications, while removing the unnecessary complexities of the underlying system libraries like Direct3D and OpenGL.
The Interverse is the evolution and combination of the Web, chat, instant messaging (IM), and voice communication. It is not just a graphical user interface (GUI), but an immersive user interface (IUI). The Interverse is a virtual universe running on top of the Internet. It uses the Crystal Space 3D engine to render the user's view of the world.
Ayam is a free 3D modelling environment for the RenderMan interface. It features good RIB export, CSG (all RenderMan primitives supported), and NURBS modelling. Features instancing, arbitrary number of modeling views, object clipboard, independent property clipboard, n-level undo, console, and Tree-View with Drag-and-Drop support.
BRL-CAD is a powerful constructive solid geometry solid modeling system that includes an interactive geometry editor, ray-tracing support for rendering and geometric analysis, path-tracing for realistic image synthesis, network distributed framebuffer support, and image and signal-processing tools.
Doom was the classic 3D shoot'em'up game from id Software. PrBoom is a game engine for playing Doom levels, which runs on both Windows and Linux/Unix systems. It uses the SDL graphics library. PrBoom a very faithful Doom port, with great effort taken to be compatible with as many original Doom levels and demos as possible.