GNU TeXmacs is a free wysiwyw (what you see is what you want) editing platform with special features for scientists. The software aims to provide a unified and user friendly framework for editing structured documents with different types of content: text, mathematics, graphics, interactive content. TeXmacs can also be used as an interface to many external systems for computer algebra, numerical analysis, and statistics. New presentation styles can be written by the user and new features can be added to the editor using Scheme.
FramerD is a semi-structured object database integrated with a Scheme-based scripting language which supports multi-lingual programming (with pervasive Unicode), a stable module system for programming in the large, distributed applications (via an extensible RPC protocol), non-deterministic (PROLOG-like) evaluation for search and set operations, multi-threaded program execution, extensive tools for text and language analysis, built-in HTML/XML/MIME parsers, and intuitive (CGI- and FastCGI-based) Web scripting. The built-in object database robustly supports millions of objects and indexed access to those objects, both through disk files and networked servers.
Eleven is a programming language for creating robust, scalable Web applications quickly and easily. It offers a 20x programmer productivity increase over traditional server programming languages like ASP, PHP, and JSP by automating state management and taking control of the application's look and feel. From high-level source code with a simple, C-like syntax, the compiler generates complete, ready-to-run implementations in PHP or mod_perl. Applications maintain their state in a relational database and are inherently fault-tolerant, secure, and scalable.
Coq au Vin is a blogging engine written in Chicken Scheme. It is designed to appeal to users who have basic Web development skills (i.e., who know HTML and CSS), are able to install their own server-side software, and would rather edit a template than press 105 buttons to customize their sites.