Thunderbird is a total redesign of the Mozilla mail component to produce a cross-platform, stand-alone mail application using the XUL user interface language. It has many new features, among them the ability to customize your toolbars the way you want them. a new look and feel with a large number of downloadable themes which alter the appearance of the client, and the ability to add UI extensions.
aria2 is a utility for downloading files. The supported protocols are HTTP(S), FTP, BitTorrent, and Metalink. It has a powerful segmented downloading ability, downloading a file from multiple sources and multiple protocols and utilizing your download bandwidth to the maximum. It supports downloading a file from HTTP(S)/FTP and BitTorrent at the same time, while the data downloaded from HTTP(S)/FTP is uploaded to the BitTorrent swarm. Using Metalink's chunk checksums, aria2 automatically validates chunks of data while downloading a file like BitTorrent.
Roundcube Webmail is a browser-based, multilingual IMAP client with an application-like user interface. It provides the full functionality you expect from an email client, including MIME support, address book, and folder manipulation. High extensibility is granted by the plugin API and the user interface is fully skinnable using XHTML and CSS 2.
AfterLogic WebMail Lite PHP is a Webmail script with a modern AJAX interface. It supports IMAP accounts, SMTP, and SSL (including Gmail). Users can check and send mail and use an address book. It provides a slick skin, a three-pane view, non-English language support, UTF-8 support, IMAP folders, and viewing and composing HTML mail. A MySQL backend is supported, with Web-based administration and installation and cPanel/Plesk/DirectAdmin integration.
LottaNZB aims to simplify and automate downloading of binary news from Usenet. You can tell it what to download using NZB files, which are created by many Usenet search engines. It integrates nicely with GNOME desktops, but is not limited to them, and uses the mature SABnzbd software as its foundation.
PeerProject is a versatile peer-to-peer filesharing client and file manager. It's intuitive and aesthetic while supporting many networks and features, including BitTorrent, G2, Gnutella, eDonkey, DC++, IRC, HTTP/FTP, and more. It's a mainstream fork of Shareaza p2p, for Windows and WINE.
Insight Server is a Linux-based email server utilizing open source components to provide a highly reliable, scalable, and cost effective email solution for customers of all sizes. It's designed to facilitate complete messaging and collaboration capabilities within a company. It supports all standard protocols, and provides backup and recovery tools, server redundancy, migration tools, and resource management.