Blender is a free 3D animation studio. It includes tools for modeling, sculpting, texturing (painting, node-based shader materials, or UV mapped), UV mapping, rigging and constraints, weight painting, particle systems, simulation (fluids, physics, and soft body dynamics and an external crowd simulator), rendering, node-based compositing, and non linear video editing, as well as an integrated game engine for real-time interactive 3D, and game creation and playback with cross-platform compatibility.
PyParticles is a particle simulation toolbox entirely written in Python. It simulates a particle-by-particle model with the most popular integrations methods, including Euler, Runge Kutta, and Midpoint. It represents the results on an OpenGL or Matplotlib plot, and offers an easy-to-use API.