3DJ is a 3D engine for writing 3D graphics applications in Python with the Pygame package. It has a rotating camera and aims to allow developers to write games with the ease of coding them in Python.
Tanir's quest is a pygame-based dungeoneering game with pluggable graphics and so on. It features a codebase of 8 rooms which can be easily extended for making a Zelda or Ultima lookalike game.
A web-based account manager for LDAP directories.
An IDE for HTML, Bash, Perl, PHP, C, etc.