SpamCheetah is a network-level spam filtering solution built around OpenBSD greylisting, tarpit, and blacklisting. It comes with a Web interface and requires zero administration. It does not allow spam to even land in your network, thus saving you precious bandwidth. It does not have the 'false positives' problem of losing legitimate mail.
Rspamd is an anti-spam system designed to work faster than SpamAssassin by using the event model and various optimizations. Its most important features include regexp and Lua rules for filtering different parts of messages, a number of built-in functions for analyzing messages, fuzzy hash support, SURBL filters, email and character table support, a control interface for remote managing and stats gathering, a Lua plugin system, statistics support (OSB/Bayes), and an AJAX-based Web interface.