cxmon is an interactive command-driven file manipulation tool inspired by the "Amiga Monitor" by Timo Rossi. It has commands and features similar to a machine code monitor/debugger, but it lacks any functions for running/tracing code. There are, however, built-in PowerPC, 680x0, 80x86, 6502 and Z80 disassemblers and special support for disassembling MacOS code. cxmon is primarily intended for emulation development but it can be used as a generic tool for manipulating and analyzing binary data and machine code, or just as a hex calculator.
MDK (MIX Development Kit) provides tools for developing and executing, in a MIX virtual machine, MIXAL programs. The MIX is Donald Knuth's mythical computer, described in the first volume of The Art of Computer Programming, which is programmed using MIXAL, the MIX assembly language. MDK includes a MIXAL assembler (mixasm), a MIX virtual machine (mixvm) with a command line interface, a Guile-based virtual machine (mixguile), a GTK+ based GUI (gmixvm), and a mixvm-Emacs interface (mixvm.el). MDK utilities are extensible using Scheme.
spim is a self-contained software simulator for running R2000/R3000 assembly language programs. It reads and can immediately execute files containing assembly language code. spim also provides a debugger and simple set of operating system services. spim provides both a simple, textual interface and a fancier, graphical interface. The package includes complete source code and documentation.
Virtual X68000 is a virtual machine that emulates a Sharp X68000 and optionally its DOS API. It will eventually run application programs for X68000 without any proprietary software including ROM BIOS, but currently lacks many key functions and is still in early development phase. Virtual X68000 is written in C++, and uses templates to implement instruction handlers.
Wine is an implementation of the Windows API on top of X and Unix. It does not require Microsoft Windows, but can use native Windows DLLs if they are available. It provides both a development toolkit for porting Windows source code to Unix as well as a program loader, allowing many unmodified Windows programs to run on x86-based Unixes.