CMUCL is a free, high performance implementation of the Common Lisp programming language which runs on most major Unix platforms. It mainly conforms to the ANSI Common Lisp standard. CMUCL provides a sophisticated native code compiler; a powerful foreign function interface; an implementation of CLOS; the Common Lisp Object System; which includes multimethods and a metaobject protocol; a source-level debugger and code profiler; and an Emacs-like editor implemented in Common Lisp. CMUCL is maintained by a team of volunteers collaborating over the Internet, and is mostly in the public domain.
ILISP is a package that is designed to integrate various Lisp implementations (mostly Common Lisp systems and various Scheme dialects, including Guile) within Emacs (or XEmacs). ILISP runs an inferior Lisp process (in Emacs parlance) and provides a specialized set of commands, key bindings, and menus to ease the interaction with it. ILISP commands access the underlying Lisp process and provide ways to make the editing, compilation, and execution of Lisp programs much easier.
SLIME is an integrated development environment for Common LISP which does everything you would expect from an IDE: code evaluation, compilation, macro expansion, and auto-completion. It also finds definitions of functions, and marks LISP forms which the compiler finds to be erroneous. It provides easy access to implementation-specific online documentation as well as the ability to look up symbols in the ANSI Common Lisp HyperSpec. Further, it includes an interactive debugger and object inspector.