Makeflow is a workflow engine for executing large complex applications on clusters, clouds, and grids. It can be used to drive several different distributed computing systems, including Condor, SGE, and the included Work Queue system. It does not require a distributed filesystem, so you can use it to harness whatever collection of machines you have available. It is typically used for scaling up data-intensive scientific applications to hundreds or thousands of cores.
Hados stores files in a cluster of servers. Its goal is to handle high availability by storing copies of the same file on several nodes. It provides RESTFUL APIs to easily store, check, or retrieve files. Using the cluster APIs, you can retrieve files from whichever node hosts them. To avoid any single point of failure, it is possible to apply a request to any node of the cluster; there is no master node.