PyMei is a Python media center application. It's designed to run as a full screen application on an HTPC, navigated by a keyboard or an LIRC input device. It plays videos or shows other types of media using external programs like mplayer. With its plugin support and themeability, it's aiming to be a very extensible and customizable media interface.
Smitten differs from traditional media centres in three major ways. It contains no media playback at all, which makes it very small (and suitable for porting to embedded systems) and quick to initialize. It targets a TV display and interface, which means there's less information on any particular screen, and a much simpler control interface consisting of left, right, up, down, and select. No mouse is required. It is also highly skinnable, and cross-platform to most systems. Essentially, it provides an easy-to-use menu system that allows the user to navigate a hierarchy of files, and view them using an (external) tool.