CIL is a frontend for the C programming language which facilitates program analysis and transformation. CIL will parse and typecheck a program, and compile it into a simplified subset of C. For example, in CIL, all looping constructs are given a single form and expressions have no side effects. This reduces the number of cases which must be considered when manipulating a C program. CIL has been used for a variety of projects, including CCured, a tool which makes C programs memory safe. It supports ANSI C, as well as most of the extensions of the GNU C and Microsoft C compilers. A Perl script acts as a drop-in replacement for either gcc or Microsoft's cl, and allows merging of the source files in your project. Other features include support for control-flow and points-to analyses.
Felix is a programming language with a fully featured purely functional subsystem embedded in a a traditional Algol-like imperative programming system. The system features garbage collection, static typing, parametric polymorphism, overloading, regular expression matching, and a lot more. A scripting harness is used to invoke source files, but fully compiled binary shared libraries are generated, yielding both rapid prototyping and high performance. Seamless binding of C/C++ code makes interfacing existing libraries easy. Control inversion provides language-level cooperative multi-tasking.
GODI provides an advanced programming environment for the Objective Caml (O'Caml) language. From INRIA (who created O'Caml) you can get the O'Caml compiler and runtime system, but this is usually not enough to develop applications. You also need libraries, and there are many developers providing them. But it is a lot of work to build and install them. GODI is a system that simplifies this task: It is a framework that automatically builds the O'Caml core system, and additionally installs a growing number of pre-packaged libraries. For a number of reasons, GODI is a source-code based system, and there are no precompiled libraries, but it makes it very simple for everybody to compile them.
CDuce is a programming language adapted to writing safe and efficient applications that manipulate XML documents. A type system checks at compile time that applications deal with all the possible inputs and produce only valid outputs. Pattern matching is a powerful operation based on regular expressions to inspect documents. CDuce also features general-purpose features; it is a higher-order functional language, with a type-safe interface with Objective Caml.