GNU TeXmacs is a free wysiwyw (what you see is what you want) editing platform with special features for scientists. The software aims to provide a unified and user friendly framework for editing structured documents with different types of content: text, mathematics, graphics, interactive content. TeXmacs can also be used as an interface to many external systems for computer algebra, numerical analysis, and statistics. New presentation styles can be written by the user and new features can be added to the editor using Scheme.
Beast is a powerful music composition and modular synthesis application. It offers multiple input methods like multitrack, piano roll, and pattern editing and supports skins. On the technical side, it has a wide range of abilities like sequencing, unlimited undo/redo history, real-time synthesis with multiprocessor support, full duplex 32-bit audio rendering, precise timing down to sample granularity, on demand loading of partial wave files, on the fly decoding of various sample formats, aliasing free oscillators, and full Scheme scripting support.
AutoGen is a tool designed for generating program files that contain repetitive text with varied substitutions. Its goal is to simplify the maintenance of programs that contain large amounts of repetitious text. This is especially valuable if there are several blocks of such text that must be kept synchronized. Output is specified with a Scheme-enhanced output template. Input, if required by your template, may come from AutoGen definitions, CGI data, or XML files.
mu is a collection of utilities for maildirs, in particular for indexing and searching them. mu fills a database with information about your emails, which can then be queried using an easy query language. It can work stand-alone or be integrated with a mail client. It also provides an emacs-based email client ("mu4e") and bindings for Guile/Scheme.
Thousand Parsec is a turn-based space empire building game, as well as a framework for creating a similar group of games, which are often called 4X games (eXplore, eXpand, eXploit, and eXterminate). Some examples of games from which Thousand Parsec draws ideas are Reach for the Stars, Stars!, VGA Planets, Master of Orion, and Galactic Civilizations. Unlike commercial alternatives, it is designed for long games supporting universes as large as your computer can handle. It allows a high degree of player customization, and features a flexible technology system where new technologies may be introduced mid-game.
QuantLib is a cross-platform, quantitative finance C++ library for modeling, pricing, trading, and risk management in real-life. It is also wrapped as Python/Ruby/Scheme modules. Extensions for Excel, R, and Mathematica are available. Other such extensions are under consideration. QuantLib offers tools that are useful both for practical implementation and for advanced modeling. It features market conventions, yield curve models, solvers, PDEs, Monte Carlo (low-discrepancy included), exotic options, VAR, and so on.
InteLib is a library of C++ classes that lets you do Lisp/Scheme programming within your C++ programs, even without any additional preprocessing, without all those calling conventions. You can write code that is accepted by a C++ compiler while thinking in a "Lisp/Scheme mode", and the code you write will look much like Lisp/Scheme code, although it will be pure C++.