CloudUSB is an OS package that is intended to boot from a USB stick or other mutable removable media. Its purpose is to let you carry your whole computing environment in your pocket and let you use any computer available as if it were your own. It stores your personal data in encrypted form on the same medium as the OS and in an online storage space, thus granting you security and privacy. Local and remote data are synchronized, allowing work to continue even offline. CloudUSB currently uses Ubuntu as the OS and Dropbox as the online storage service.
Whonix is an anonymous general-purpose operating system based on Virtual Box, Debian GNU/Linux, and Tor. By design, IP and DNS leaks are impossible. Not even malware with root rights can find out the user's real IP/location, because Whonix consists of two (virtual) machines. One machine solely runs Tor and acts as a gateway, called Whonix-Gateway. The other machine, Whonix-Workstation, is on a completely isolated network. Only connections through Tor are possible.