Songwrite is a tablature editor. It supports many string instruments in addition to traditional staff notation. You can edit tablature (guitar, bass, banjo, etc.) and staff notation, add lyrics, create your own songbook, play your partitions, print your partitions and your songs, automatically convert staff notation to tablature and vice-versa, export songs to many formats (PDF, MIDI, ASCII tablature, GNU Lilypond, LaTeX, PostScript, etc.), and import Guitar Pro 3/4 files (experimental).
Tux Paint is a simple and entertaining drawing program geared towards young children. It has a simple interface, sound effects, and a cartoon character (Tux, the Linux penguin). Along with drawing brush strokes, lines and shapes, you can also enter text and place "rubber stamp" (or "sticker") images on the picture. Tux Paint is extensible, and could be useful in an educational environment (such as a grammar, elementary, or grade school). It's portable across numerous platforms, and runs well even on slower systems like the Pentium 133MHz.
WebEdit Professional is a simple and powerful browser-based application that enables any non-technical user to create, edit, and manage their entire website. It features access control, file management capabilities, and the ability to edit and create new files within a WYSIWYG editor, and templates.
LiquidMaya is a Maya to Renderman plug-in that handles full Renderman output support with a focus on speed, efficiency, and extensibility. Its features include procedural rib generation, full network rendering support, segmented rib files, a shader assignment interface, and much more. Along with the ability to write full C++ plug-ins, it is incredibly easy to script Liquid with Mel. Liquid was used for the visual effects of the "Lord of the Rings" movie.
Audiality is a highly scalable and portable audio engine and synthesizer. MIDI files are used in combination with scripting and modular synthesis, to minimize file sizes and maximize flexibility. Audiality can be used as a music and sound effects player in multimedia productions, or as a realtime MIDI synthesizer.
Csound is a powerful and yet easy to use musical synthesis package. Csound was constructed in the tradition of so-called music-N languages, among which the best-known is Music V. It consists of an orchestra- and score-driven executable, written in C for portability. Since Csound is a computational language, it is highly flexible and efficient; complexity is gained only at the expense of computation power. Basically, Csound reads some files and creates the result as a sound file on disk or, on faster machines, in real time through a DAC.
The CMU Midi Toolkit (CMT) is a collection of software for writing interactive MIDI software in C. It includes a number of handy utilities along with an application "shell" that provides timing, scheduling, and MIDI interfaces that are portable across DOS, Mac, SGI, and Amiga platforms.