FMS is a tool to create all kinds of sounds from scratch. You can play any sound (sine, triangular, vowels, etc.) with any property settings (frequency, volume, balance, sweep, etc.) and modulations thereof. It also features tools to save sounds, play .MUS music, graphically display sounds, and make real noise.
Audiality is a highly scalable and portable audio engine and synthesizer. MIDI files are used in combination with scripting and modular synthesis, to minimize file sizes and maximize flexibility. Audiality can be used as a music and sound effects player in multimedia productions, or as a realtime MIDI synthesizer.
bcr beats is a beat slicer that lets you cut up and play with an audio sample: you can trigger slices and loops with MIDI or the mouse and keyboard, set pan, volume, and sample rate values, and generally have lots of fun. The interface is based on the Behringer BCR2000 MIDI controller, which means lots of knobs. It can be used with or without a controller.