The Dextop application framework allows you to create Rich Internet Applications based on .NET/Mono and Sencha Ext JS. It has proven to be useful for online business applications. It features a desktop-like Ext JS frontend, simplified client-server communication, a stateful programming model, real-time updates and notifications from the server, automatic column model generation, automatic store model generation, and automatic form generation.
XEO (eXtensible Enterprise Objects) is an agile development framework designed for creating Web applications built around Object Oriented concepts and Model Driven Development with Java. You model business entities (including their attributes and behavior) as XEO Models which are then processed by the framework's "Builder". This produces the application's supporting structures such as database tables (to persist data) and Java classes (providing object-relational mapping and behavior). Development is supported by an Eclipse plugin called XEOStudio.