With MetaModel, you use a type-safe SQL-like API for querying any datastore. It is a data access framework providing a common interface for exploration and querying of different types of datastores. It isn't a data mapping framework. Instead, it emphasizes abstraction of metadata and the ability to add data sources at runtime, making MetaModel great for generic data processing applications, but less so for applications modeled around a particular domain.
Spring is a lightweight Java/J2EE application framework based on code published in "Expert One-on-One J2EE Design and Development" by Rod Johnson. It includes powerful JavaBeans-based configuration management applying Inversion-of-Control principles, a generic abstraction layer for transaction management allowing for pluggable transaction managers, a JDBC abstraction layer, integration with Hibernate, JDO, Apache OJB, and iBATIS SQL Maps, AOP functionality, and a flexible MVC Web application framework with multiple view technologies. There is also a .NET port available.