Thunderbird is a total redesign of the Mozilla mail component to produce a cross-platform, stand-alone mail application using the XUL user interface language. It has many new features, among them the ability to customize your toolbars the way you want them. a new look and feel with a large number of downloadable themes which alter the appearance of the client, and the ability to add UI extensions.
SOGo is a very fast and scalable modern collaboration suite (or groupware). It offers calendaring, address book management, and a full-featured Webmail client along with resource sharing and permission handling. It also makes use of documented standards (IMAP, CalDAV, CardDAV, etc.) and thereby provides native connectivity (without plugins) to many clients such as Microsoft Outlook, Apple iCal, the iPhone, Mozilla Lightning, and a plethora of mobile devices via SyncML. It can reuse any existing email and database infrastructure, avoiding long hours of site restructuring.
EGroupware is a Web-based groupware suite. It contains many modules, including Calendar (personal calendar and group scheduling, notifications and alarms), Mail (IMAP only), InfoLog (todos, notes, and phone calls linked to contacts/CRM), Contacts (an address book for storing and sharing contact information), ProjectManager, Tracker (bug or incident tracking), TimeSheet, SyncML, CalDAV & CardDAV support, and SiteMgr content management
Horde Groupware Webmail Edition is an enterprise ready browser-based communication suite. Users can read, send, and organize email messages and manage and share calendars, contacts, tasks, and notes with the standards compliant components from the Horde Project. It bundles the separately available applications IMP, Ingo, Kronolith, Turba, Nag, and Mnemo. It can be extended with any of the released Horde applications or the Horde modules that are still in development, like a file manager, a bookmark manager, a forum, or a wiki.
XFMail is an X11 application for receiving electronic mail. It implements most of its email functionality internally so that it does not depend on a lot of extra packages. It supports POP3, MBOX, IMAP4, sendmail, and SMTP. It has built-in support for interfacing with PGP, GPG, ispell/aspell, faces, LDAP, and esound. It runs on most Unix variants.
AtMail is a webmail client. The project aims to provide an elegant client for existing IMAP mailservers, with less bloat and a focus on an intuitive, simple user interface. Features include complete Webmail functionality, address-book support, video mail, an AJAX interface, drag'n'drop, and more.
Webtop is a Web-based POP3 email client that includes SSL encryption, Mozilla support, many email filter options, spam fighting features, custom folders, email import/export, fast searching, undeliverable email bounce, intelligent read receipts, and email-to-PDF generation. The Webtop also includes a calendar, notepad, online file storage, automated email reminders, contacts, mailing lists, and Web-based administration. One installation can support multiple users and each user can set up as many POP3 accounts as they need.